Fig. 2

MiR-5195-3p enhanced the paclitaxel sensitivity of breast cancer cells. a Synthesized miR-5195-3p mimics were transfected into paclitaxel-resistant MCF-7/PTX and MDA-MB-231/PTX cells. MiR-5195-3p expression was measured using quantitative real-time PCR. b and c CCK-8 assay was performed to determine the cell sensitivity to paclitaxel of MCF-7/PTX and MDA-MB-231/PTX cells. d The 50% inhibitory concentration (IC50) value of paclitaxel in MCF-7/PTX and MDA-MB-231/PTX cells transfected with mimics or miR-NC. ***p < 0.001 vs. miR-NC