Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

Table 2 Localization of gene activation sites upstream of transcription start sites of human genes SV2A, SV2B and SV2C

Transcription factor motif	Location upstream of SV2A	Location upstream of SV2B	Location upstream of SV2C
RARα	363 bp	242 bp 284 bp 645 bp	No predicted sites
RARα v.2	194 bp 330 bp 991 bp	54 bp 427 bp 486 bp 569 bp 797 bp 890 bp	255 bp 332 bp
CREB1	No predicted sites	459 bp 564 bp 952 bp	92 bp
CREB3	878 bp	No predicted sites	128 bp
CREB3L1	282 bp 576 bp 956 bp	No predicted sites	No predicted sites

Predictions were made using the Eukaryotic Promotor Database using motifs from the Transcription Factor Motifs library and possible hits with a cut-off p-value of at least 0.001 were used. Predictions were made of an area of 1000 base pairs (bp) upstream from the transcription start site

ISSN: 1689-1392